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By: Jadon Webb, M.D., Ph.D.
Treating depression can be particularly difficult for people who have had traumatic things happen to them in the past . A history of childhood trauma can make symptoms of anxiety, depression, and Post traumatic stress (PTSD) harder to treat and more medication-resistant. This has been a source of continual pain and frustration at clinics across the country trying to help. An incredible new study published in 2021 found that ketamine treatment of depression was very effective for people who had suffered childhood trauma. In fact, there is some evidence that ketamine might be even more effective at treating adult depression if an individual had suffered childhood trauma. This is similar to findings from a 2019 study, and is completely unlike any other treatments for depression which generally don't work as well for those who have suffered trauma. This study offers great hope for those who carry around ancient wounds and continue to feel sad and hopeless. We also know that ketamine can be very effective at treating PTSD symptoms that can come from trauma, making it an even better choice for some people suffering from PTSD who are also depressed. We are eager to see this work replicated from other research groups. If the finding continues to hold, this is a game changer for those with trauma in their past.
20 Comments
6/19/2025 01:47:50 am
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This is such an important resource! San Luis Obispo County Drug and Alcohol Services provides vital programs for those who might not have access to private treatment. It's great to see the county stepping up like this. 7/3/2025 07:39:50 am
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I’ve been researching rehabilitation options in Athens GA and came across some really helpful resources. If anyone’s had experience with local rehab centers here, I’d love to hear your thoughts. Finding the right support is so crucial! 7/17/2025 12:22:50 am
There are several reputable detox centers in Nashville, TN offering medically supervised detox and supportive aftercare planning. It's great to see how these centers focus on both physical recovery and mental health support. 7/17/2025 02:21:52 am
It’s amazing how far Los Angeles mental health care has come in recent years. 7/19/2025 02:25:19 am
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about the authorS
Jadon Webb, M.D., Ph.D.
Owner Bloom Mental Health 
Shannon Keane,
MSN, FNP-C, PMHNP-BC Clinical Director Disclaimer: this blog is NOT intended as medical advice and does not imply any kind of specific guidance or treatment recommendations, and should NOT be used to guide a treatment protocol. (read full disclaimer)
Afton Williamson,
DNP, MSN, FNP-BC Family Nurse Practitioner |
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