Botulinum Toxin for depression and migraines

By: Jadon Webb, M.D., Ph.D.

Botulinum toxin (Botox®) has strong research evidence as an effective treatment for depression. It appears to also be effective, perhaps even more so, in people who suffer from both depression and migraine headaches according to a 2021 meta-analysis. 
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Botulinum toxin is generally very safe, well-tolerated, and can be used in conjunction with many other psychiatric medications. While we do not specifically treat migraines in this practice, if a client needs help with depression and also happens to have migraines, botulinum treatment may incidentally help this, and be worth considering.

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